Recent Innovations in Carbon-Ion Radiotherapy
نویسندگان
چکیده
منابع مشابه
The Emerging Role of Carbon-Ion Radiotherapy
Carbon-ion radiotherapy (CIRT) has progressed rapidly in technological delivery, indications, and efficacy. Owing to a focused dose distribution in addition to high linear energy transfer and subsequently high relative biological effect, CIRT is uniquely able to target otherwise untreatable hypoxic and radioresistant disease while opening the door for substantially hypofractionated treatment of...
متن کاملCarbon-ion radiotherapy—basic and clinical studies
Radiotherapy using charged and/or high-LET particles has a long history, starting with proton beams. In vitro data clarify that RBE (Relative Biological Effectiveness) increases with LET up to approximately 150 keV/μm for carbon-12 and neon-20 ions. In vivo studies show that tumor control probabilities after single doses of gamma rays shift to higher doses when tumors were irradiated with 5-fra...
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In the three therapy beam times 2007 about 50 patients were planned and treated with our treatment planning software, TRiP98, and its development version, TRiP98BEAM. In the past, the standard method was to optimize the biological target dose distribution for the contributing partial fields singly. Due to the enormous effort for the computation of biological effects, only a simple, but still su...
متن کاملCarbon ion radiotherapy for unresectable sacral chordomas.
PURPOSE The purpose is to evaluate the efficacy and toxicity of carbon ion radiotherapy for unresectable sacral chordomas. EXPERIMENTAL DESIGN We performed a retrospective analysis of 30 patients with unresectable sacral chordomas treated with carbon ion radiotherapy at the Heavy Ion Medical Accelerator in Chiba, Japan. Twenty-three patients presented with no prior treatment, and the remainin...
متن کاملClinical advantages of carbon-ion radiotherapy
Carbon-ion radiotherapy (C-ion RT) possesses physical and biological advantages. It was started at NIRS in 1994 using the Heavy Ion Medical Accelerator in Chiba (HIMAC); since then more than 50 protocol studies have been conducted on almost 4000 patients with a variety of tumors. Clinical experiences have demonstrated that C-ion RT is effective in such regions as the head and neck, skull base, ...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2010
ISSN: 0449-3060,1349-9157
DOI: 10.1269/jrr.10028